Ohio Bobcats (1-1) vs. South Alabama Jaguars (1-1) September 19, 2026 7:00 pm EDT The Line: South Alabama Jaguars -258 / Ohio Bobcats 210; Over/Under: 49.5 (Get latest betting odds)
In this article, we will formulate a Ohio vs South Alabama Prediction for this College Football Week 3 matchup on Saturday, September 19 th . Let’s take a look at the prediction for this College Football matchup.
South Alabama has a 1-1 record and are coming off a 24-28 road loss against Tulane. They will face Kentucky and Louisiana-Monroe next. Offensively, South Alabama averages 31.5 points per game, ranking 69th in the nation, while defensively, they allow 21 points per game, which is 73rd. South Alabama averages 436.5 total yards per game (225 passing and 211.5 rushing), while allowing 327.5 total yards per game (128.5 rushing and 199 passing).
Bishop Davenport leads South Alabama with 450 passing yards with 67.8% completed passes and 3 touchdowns. PJ Martin leads the team in rushing yards with 142, while Brendan Jenkins has a team-high 14 receptions for 197 receiving yards. Defensively, Cole Blaylock has a team-high 12 total tackles (7 of them solo).
Ohio has a 1-1 record and are coming off a 29-27 home win against Jacksonville State. They will face Stonehill and Kent State next. Offensively, Ohio averages 25 points per game, ranking 95th in the nation, while defensively, they allow 38 points per game, which is 133rd. Ohio averages 282.5 total yards per game (130.5 passing and 152 rushing), while allowing 485 total yards per game (204.5 rushing and 280.5 passing).
Nick Poulos leads Ohio with 180 passing yards with 44.4% completed passes and one touchdown. Duncan Brune leads the team in rushing yards with 98, while Riley Neer has a team-high 10 receptions for 142 receiving yards. Defensively, Jack Fries has a team-high 19 total tackles (10 of them solo), while Isaac Ackerman leads the team with 2 sacks.
In this Ohio vs South Alabama Prediction, South Alabama is coming as -6.5 home favorites. Both teams are coming off opposite outcomes in their previous games with South Alabama coming off a road loss, but they have won their only home game and have better numbers both offensively and defensively. On the flip side, Ohio lost its only road game by 21-49 and have a bottom-6 defense in the entire country, so I don’t trust them to keep this one close on the road. Take South Alabama and lay the -6.5 in this one.