UConn Huskies (1-1) vs. Southern Mississippi Golden Eagles (1-1) September 19, 2026 7:00 pm EDT The Line: Southern Mississippi Golden Eagles 136 / UConn Huskies -162; Over/Under: 54.5 (Get latest betting odds)
In this article, we will formulate a UConn vs Southern Miss Prediction for this College Football Week 3 matchup on Saturday, September 19 th . Let’s take a look at the prediction for this College Football matchup.
Southern Miss has a 1-1 record this season and are coming off an 8-43 road loss against Auburn. They will face Tulane and Troy next. Offensively, Southern Miss averages 28.5 points per game, ranking 84th in the nation, while defensively, they allow 23 points per game, which is 82nd. Southern Miss averages 382 total yards per game (198.5 passing and 183.5 rushing), while allowing 418 total yards per game (223.5 rushing and 194.5 passing).
Ethan Hampton leads Southern Miss with 326 passing yards with 62% completed passes and 2 touchdowns. Steven Robinson leads the team in rushing yards with 174, while Mario Sanders II has a team-high 9 receptions for 152 receiving yards. Defensively, Laquan Robinson has a team-high 18 total tackles (12 of them solo), while Jyaire Brown leads the team with one sack.
UConn has a 1-1 record this season and are coming off a 14-38 home loss against Maryland. They will face Miami (OH) and Syracuse next. Offensively, UConn averages 35 points per game, ranking 54th in the nation, while defensively, they allow 22.5 points per game, which is 78th. UConn averages 447 total yards per game (263 passing and 184 rushing), while allowing 342 total yards per game (94.5 rushing and 247.5 passing).
Kalieb Osborne leads UConn with 421 passing yards with 61.7% completed passes and 4 touchdowns. He also leads the team in rushing yards with 120, while Javon Brown has a team-high 6 receptions for 92 receiving yards. Defensively, Zion Paret has a team-high 15 total tackles (9 of them solo), while Anas Luqman leads the team with one sack.
In this UConn vs Southern Miss Prediction, UConn is coming as -3.5 road favorites. Both teams are coming off their first defeats of the season, as they lost badly in their only games played against FBS teams, losing by 24 and 35 points respectively. They also looked terrible offensively in those two games, scoring 14 and 8 points and I don’t expect them to flip the switch and break out offensively. Take the under 54.5 points in this one.