LA Angels (12-19) vs. Chicago White Sox (13-17) April 29, 2026 1:10 pm EDT The Line: Chicago White Sox 104 / LA Angels -126; Over/Under: 8.5 (Get latest betting odds)
In this article, we will formulate an Angels vs White Sox Prediction for this MLB matchup on Wednesday, April 29 th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The Chicago White Sox have a 13-17 record this season and are sitting in the third place of the AL Central. They have a 6-8 home record and are coming off a 5-2 home win against the Angels. Their previous three games were an 8-7 home win against the Angels , a 1-2 and a 3-6 home loss against the Nationals .
The White Sox have a .225 batting average this season, .318 OBP and .383 Slugging percentage. Chicago’s pitching staff has a 4.59 ERA and 1.45 WHIP. Chase Meidroth is the team’s best hitter with a .257 batting average. Munetaka Murakami leads the team in RBI with 23, also adding a team‑high 12 home runs.
Erick Fedde (R) is the projected starting pitcher for the White Sox, and he has a 0-3 record, 3.42 ERA and 1.14 WHIP.
The Los Angeles Angels have a 12-19 record this season and are sitting in the fourth place of the AL West. They have a 7-12 away record and are coming off a 2-5 road loss against the White Sox. Their previous three games were a 7-8 road loss against the White Sox, a 9-11 and a 1-12 road loss against the Royals.
The Angels have a .238 batting average this season, .337 OBP and .399 Slugging percentage. Los Angeles’ pitching staff has a 4.63 ERA and 1.44 WHIP. Jo Adell is the team’s best hitter with a .262 batting average. Jorge Soler leads the team in RBI with 23, and Mike Trout adds a team‑high 9 home runs.
Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 0-3 record, 6.21 ERA and 1.59 WHIP.
The White Sox are 4-1 in their last 5 meetings against the Angels and are 5-2 in their last 7 meetings in Chicago.
In this Angels vs White Sox Prediction, the Angels are coming as -125 road favorites. Since the Angels cannot win with Soriano on the mound like yesterday, I will fade them as road favorites. Kikuchi has been bad this season and has 4+ earned runs in four of his last five starts and has been terrible on the road. Fedde has been better at home for the White Sox, who have both a better bullpen and are better against lefties. Take the White Sox on the moneyline at home for plus money.