San Francisco Giants (20-27) vs. Arizona Diamondbacks (22-23) May 18, 2026 9:40 pm EDT The Line: Arizona Diamondbacks -142 / San Francisco Giants +118; Over/Under: 9 (Get latest betting odds)
The San Francisco Giants and the Arizona Diamondbacks meet Monday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Giants vs. Arizona Diamondbacks prediction.
The San Francisco Giants will send out Robbie Ray for the start here and Ray is 3-5 with a 3.04 ERA and 49 strikeouts this season. In his career, Ray is 3-0 with a 3.15 ERA and 21 strikeouts against Arizona. Zac Gallen will start here for Arizona and is 1-4 with a 5.02 ERA and 29 strikeouts this season. In his last five starts against San Francisco, Gallen is 4-1 with a 2.27 ERA and 38 strikeouts.
The San Francisco Giants come into this game looking to add on to their 10-1 win over the Athletics last time out to improve to 20-27 this season. After this series, the Giants will square off against the Chicago White Sox at home.
Luis Arraez has 57 hits with 9 doubles, 2 triples and 16 RBIs while Willy Adames has 44 hits with 14 doubles, 3 home runs and 13 RBIs along with 56 strikeouts. Matt Chapman has 39 hits with 11 doubles, a triple, a home run and 16 RBIs and Jung Hoo Lee has 47 hits with 10 doubles and 17 RBIs. Heliot Ramos has 44 hits with 12 doubles, 4 home runs and 20 RBIs this season. Rafael Devers also has 44 hits with 10 doubles, 5 home runs and 19 RBIs but also has 59 strikeouts this season.
The Arizona Diamondbacks come into this game looking to add on to their 8-6 win over Colorado last time out to sit at 22-23 this season. After this series, the Diamondbacks will take on the Rockies in a series rematch at home.
Corbin Carroll has 42 hits including 11 doubles, 4 triples, 7 home runs and 24 RBIs while Alek Thomas has logged 9 doubles with 2 home runs and 10 RBIs as well this season. Ketel Marte has 36 hits with 6 doubles, 5 home runs and 15 RBIs and Geraldo Perdomo has 33 hits, with 7 doubles, 3 triples, 2 home runs and 12 RBIs as well this season. Nolan Arenado also has 39 hits with 7 doubles, 6 home runs and 21 RBIs and Jose Fernandez has 33 hits with 3 home runs and 14 RBIs this season. Ildemaro Vargas also has 51 hits with 8 doubles, 2 triples, 7 home runs and 31 RBIs.
I’m on the Giants in this one. I think that the Giants have an edge here in starting pitching with Robbie Ray going as Ray was solid prior to the start against the Dodgers, which I’m not going to fault anyone for having a rough outing against that Dodger lineup. Zac Gallen’s been getting roughed up in recent starts and I think the Giants draw first blood here. Give me San Francisco.