Houston Astros (52-54) vs. Chicago White Sox (54-49) July 26, 2026 2:10 pm EDT The Line: Chicago White Sox -114 / Houston Astros -105; Over/Under: 9.5 (Get latest betting odds)
In this article, we will formulate a Astros vs White Sox Prediction for this MLB matchup on Sunday, July 26 th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The Chicago White Sox have a 54-49 record this season and are sitting in the 1st place of the AL Central. They have a 31-19 home record and are coming off a 1-4 home loss against the Astros. They will face the Yankees and the Rays next.
The Chicago White Sox have a .239 batting average this season, .317 OBP and .406 Slugging percentage. Chicago’s pitching staff has a 4.12 ERA and 1.31 WHIP. Sam Antonacci is the team’s best hitter with a .278 batting average. Miguel Vargas leads the team in RBI with 61, while Colson Montgomery adds a team-high 24 home runs.
Erick Fedde (R) is the projected starting pitcher for the Chicago White Sox, and he has a 5-6 record, 4.16 ERA and 1.40 WHIP.
The Houston Astros have a 52-54 record this season and are sitting in the 2nd place of the AL West. They have a 26-27 away record and are coming off a 4-1 road win against the White Sox. They will face the Angels and the Rangers next.
The Houston Astros have a .242 batting average this season, .316 OBP and .412 Slugging percentage. Houston’s pitching staff has a 4.67 ERA and 1.38 WHIP. Yordan Alvarez is the team’s best hitter with a .325 batting average, leads the team in RBI with 77, and adds a team-high 34 home runs.
Ronel Blanco (R) is the projected starting pitcher for the Houston Astros, and he has a 0-0 record, 7.71 ERA and 1.07 WHIP.
The Astros are 7-3 in their last 10 meetings against the White Sox and are 3-1 in their last 4 visits in Chicago.
In this Astros vs White Sox Prediction, the White Sox are coming as -115 home favorites. I like the White Sox at home in this one as they are looking to avoid the series sweep. Erick Fedde has been very good at home with a 2.91 ERA, while Ronel Blanco gave up 4 runs in his season debut for the Astros. The White Sox have both a better offense and a better bullpen and I expect them to win this one at home.