Houston Astros (50-54) vs. Chicago White Sox (54-47) July 24, 2026 7:40 pm EDT The Line: Chicago White Sox -136 / Houston Astros 113; Over/Under: 8.5 (Get latest betting odds)
In this article, we will formulate a Astros vs White Sox Prediction for this MLB matchup on Friday, July 24 th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
The Chicago White Sox have a 54-47 record this season and are sitting in the 1st place of the AL Central. They have a 31-17 home record and are coming off a 4-2 road win against the Rangers. They will face the Yankees and the Rays next.
The Chicago White Sox have a .240 batting average this season, .318 OBP and .409 Slugging percentage. Chicago’s pitching staff has a 4.08 ERA and 1.31 WHIP. Sam Antonacci is the team’s best hitter with a .278 batting average. Miguel Vargas leads the team in RBI with 61, while Colson Montgomery adds a team-high 24 home runs.
Davis Martin (R) is the projected starting pitcher for the Chicago White Sox, and he has a 9-5 record, 3.31 ERA and 1.27 WHIP.
The Houston Astros have a 50-54 record this season and are sitting in the 3rd place of the AL West. They have a 24-27 away record and are coming off a 5-2 home win against the Marlins. They will face the Angels and the Rangers next.
The Houston Astros have a .242 batting average this season, .315 OBP and .413 Slugging percentage. Houston’s pitching staff has a 4.71 ERA and 1.39 WHIP. Yordan Alvarez is the team’s best hitter with a .328 batting average, leads the team in RBI with 77, and adds a team-high 34 home runs.
Spencer Arrighetti (R) is the projected starting pitcher for the Houston Astros, and he has a 7-5 record, 4.34 ERA and 1.31 WHIP.
Both teams are tied 3-3 in their last 6 meetings and are 2-2 in their last 4 meetings in Chicago.
In this Astros vs White Sox Prediction, the White Sox are coming as -130 home favorites. I like the White Sox in this one at home with Davis Martin on the bump, who has been elite when pitching in Chicago, with a 5-1 record and 1.80 ERA. On the flip side, Spencer Arrighetti has been all over the place lately, alternating one run games with 8-run games, so I certainly don’t trust them, especially on the road. The White Sox are one of the best home teams in baseball and are 7-2 in their last 9 games, while having both a better offense and a better bullpen. Take the White Sox to win this one.