Milwaukee Brewers (95-58) vs. Baltimore Orioles (75-78) September 18, 2026 7:05 pm EDT The Line: Baltimore Orioles 119 / Milwaukee Brewers -144; Over/Under: 8.5 (Get latest betting odds)
In this article, we will formulate a Brewers vs Orioles Prediction for this MLB matchup on Friday, September 18 th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
The Baltimore Orioles have a 75-78 record this season and are sitting in the 5th place of the AL East. They have a 36-39 home record and are coming off a 7-1 road win against the Mets. They will face the Blue Jays and the Yankees next.
The Baltimore Orioles have a .234 batting average this season, .315 OBP and .396 Slugging percentage. Baltimore’s pitching staff has a 4.14 ERA and 1.35 WHIP. Pete Alonso is the team’s best hitter with a .267 batting average, leading the team in RBI with 102 and adding a team-high 37 home runs.
Cade Povich (L) is the projected starting pitcher for the Orioles, and he has a 2-1 record, 4.05 ERA and 1.44 WHIP.
The Milwaukee Brewers have a 95-58 record this season and are sitting in the 1st place of the NL Central. They have a 43-32 away record and are coming off a 7-4 road loss against the Pirates. They will face the Phillies and the Cardinals next.
The Milwaukee Brewers have a .259 batting average this season, .342 OBP and .405 Slugging percentage. Milwaukee’s pitching staff has a 3.58 ERA and 1.19 WHIP. Jackson Chourio is the team’s best hitter with a .286 batting average. Brice Turang leads the team in RBI with 93, while Jake Bauers adds a team-high 26 home runs.
Dustin May (R) is the projected starting pitcher for the Brewers, and he has a 7-9 record, 4.49 ERA and 1.29 WHIP.
The Brewers are 7-3 in their last 10 meetings against the Orioles and are 3-1 in their last 4 visits in Baltimore.
In this Brewers vs Orioles Prediction, the Brewers are coming as -140 road favorites. I don’t like the pitching in this matchup, as both starters have a 4+ ERA and Dustin May sits on a 5.50 road ERA this season. Both offenses have been red-hot lately, especially Milwaukee’s and they both average 12.5 runs per game combined in their last 10 games and as a result, they are 12-4 to the over in their last 16 games combined. Take the over 8.5 in this one.