St. Louis Cardinals (13-8) vs. Miami Marlins (10-12) April 20, 2026 6:40 pm EDT The Line: Miami Marlins -136 / St. Louis Cardinals 113; Over/Under: 8.5 (Get latest betting odds)
In this article, we will formulate a Cardinals vs Marlins Prediction for this MLB matchup on Monday, April 20 th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
The Miami Marlins have a 10-12 record this season and are sitting in the second place of the NL East. They have a 8-5 home record and are coming off a 5-3 home win against the Brewers. Their previous three games were a 2-5 and a 5-7 home loss against the Brewers, and a 3-6 road loss to the Braves.
The Marlins have a .255 batting average this season, .329 OBP and .391 Slugging percentage. Miami’s pitching staff has a 4.06 ERA and 1.27 WHIP. Otto Lopez is the team’s best hitter with a .338 batting average. Liam Hicks leads the team in RBI with 19, also adding a team‑high 4 home runs.
Max Meyer (R) is the projected starting pitcher for the Marlins, and he has a 1-0 record, 4.12 ERA and 1.32 WHIP.
The St. Louis Cardinals have a 13-8 record this season and are sitting in the second place of the NL Central. They have a 6-3 away record and are coming off a 7-5 road win against the Astros. Their previous three games were a 7-5 and a 9-4 road win against the Astros, and a 5-3 home win against the Guardians.
The Cardinals have a .233 batting average this season, .328 OBP and .379 Slugging percentage. St. Louis’ pitching staff has a 4.83 ERA and 1.41 WHIP. Jordan Walker is the team’s best hitter with a .305 batting average, also leading the team in RBI with 16 and adding a team‑high 8 home runs.
Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 1-1 record, 2.49 ERA and 0.83 WHIP.
The Marlins are 5-3 in their last 8 meetings against the Cardinals but both teams are tied 3-3 in their last six meetings in Miami.
In this Cardinals vs Marlins Prediction, the Marlins are coming as -135 home favorites. Both teams are coming into this matchup in opposite trajectories, as the Cardinals have five consecutive wins and are coming off a series sweep against the Astros where they scored 23 runs in three games. On the flip side, the Marlins are 2-7 in their last 9 games and have 6+ earned runs in five of their last eight games. McGreevy has been looking great for the Cardinals so far, so I like the value with the road dog in this spot. Take the Cardinals on the moneyline for plus money.