St. Louis Cardinals (65-63) vs. Cincinnati Reds (61-66) August 20, 2026 12:40 pm EDT The Line: Cincinnati Reds 104 / St. Louis Cardinals -112; Over/Under: 9 (Get latest betting odds)
In this article, we will formulate a Cardinals vs Reds Prediction for this MLB matchup on Thursday, August 20 th in the fifth game of this series. Let’s take a look at the prediction for this MLB matchup.
The Cincinnati Reds have a 61-66 record this season and are sitting in 5th place in the NL Central. They have a 32-35 home record and are coming off a 5-4 home win against the Cardinals. They will face the Diamondbacks and the Giants next.
The Cincinnati Reds have a .226 batting average this season, a .305 OBP, and a .391 slugging percentage. The Reds’ pitching staff has a 4.48 ERA and a 1.40 WHIP. Elly De La Cruz leads the Reds with a .259 batting average. Sal Stewart leads the team in RBI with 94 and adds a team-high 27 home runs.
Brady Singer (R) is the projected starting pitcher for the Reds, and he has a 5-11 record, a 4.66 ERA, and a 1.44 WHIP.
The St. Louis Cardinals have a 65-63 record this season and are sitting in 3rd place in the NL Central. They have a 33-29 road record and are coming off a 4-5 road loss against the Reds. They will face the Phillies and the Orioles next.
The St. Louis Cardinals have a .241 batting average this season, a .317 OBP, and a .382 slugging percentage. The Cardinals’ pitching staff has a 4.01 ERA and a 1.32 WHIP. Alec Burleson leads the Cardinals with a .289 batting average and a team-high 92 RBI, while Jordan Walker adds a team-high 25 home runs.
Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 5-9 record, a 3.48 ERA, and a 1.22 WHIP.
Both teams are tied 4-4 in their last 8 meetings and are 2-2 in their last 4 meetings in Cincinnati.
In this Cardinals vs Reds Prediction, the Cardinals are coming as -115 road favorites. I don’t like the pitching in this matchup as both starters have 5+ expected ERA and have been in bad form lately. Singer has given up 3+ runs in each of his last five starts and McGreevy 3+ runs in three of his last five. The Reds have the 6 th -worst bullpen ERA in baseball and two of their last three meetings in this series had at least nine total runs. Take the over 9 in this one.