St. Louis Cardinals (4-4) vs. Detroit Tigers (4-4) April 5, 2026 7:20 pm EDT The Line: Detroit Tigers -143 / St. Louis Cardinals 119; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Cardinals vs Tigers Prediction for this MLB matchup on Sunday, April 5 th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The Detroit Tigers have a 4-4 record this season and are sitting in the third place of the AL Central. They have a 2-0 home record and are coming off an 11-6 home win against the Cardinals. Their previous three games were a 4-0 home win against the Cardinals, and a 0-1 road loss and a 5-7 road loss against the Diamondbacks.
The Tigers have a .247 batting average this season, .329 OBP and .384 Slugging percentage. Detroit’s pitching staff has a 3.61 ERA and 1.28 WHIP. Colt Keith is the team’s best hitter with a .417 batting average. Dillon Dingler leads the team in RBI with 7, also adding a team-high two home runs.
Keider Montero (R) is the projected starting pitcher for the Tigers and last season he had a 6-6 record, 4.76 ERA and 1.33 WHIP.
The St. Louis Cardinals have a 4-4 record this season and are sitting in the fourth place of the NL Central. They have a 0-2 road record and are coming off a 6-11 road loss against the Tigers. Their previous three games were a 0-4 road loss against the Tigers, and a 2-1 home win and a 3-0 home win against the Mets.
The Cardinals have a .220 batting average this season, .299 OBP and .352 Slugging percentage. St. Louis’ pitching staff has a 5.18 ERA and 1.58 WHIP. Victor Scott II is the team’s best hitter with a .308 batting average. Jordan Walker leads the team in RBI with 8, and Nolan Gorman adds a team-high two home runs.
Kyle Leahy (R) is the projected starting pitcher for the Cardinals, and he has a 0-1 record, 7.20 ERA and 2.00 WHIP.
The Tigers are 6-1 in their last 7 meetings against the Cardinals, having won their last four meetings in Detroit.
In this Cardinals vs Tigers Prediction, the Tigers are coming as -140 home favorites. The Tigers have been dominating the Cardinals in this series, having won both games with a combined 15-6 score, but I’m not rushing to back Montero as a starter, as he had been shaky last season and weaker at home with a 4.85 ERA. The Cardinals are starting with a reliever and have the 8 th -worst bullpen ERA in baseball, so I don’t trust either side and I will take the over 8 runs in this one.