Washington Nationals (1-1) vs. Chicago Cubs (1-1) March 29, 2026 2:20 pm EDT The Line: Chicago Cubs -252 / Washington Nationals +203; Over/Under: 9.5 (Get latest betting odds)
The Washington Nationals and the Chicago Cubs meet Sunday in MLB action from Wrigley Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Washington Nationals vs. Chicago Cubs prediction.
The Washington Nationals will send out Jake Irvin for the start here and Irvin was 9-13 with a 5.70 ERA and 124 strikeouts last season. In his last five starts against the Cubs, Irvin is 0-4 with a 9.70 ERA and 17 strikeouts. Shota Imanaga will start for the Cubs here and was 9-8 with a 3.73 ERA and 117 strikeouts last season.
The Washington Nationals come into this game looking to bounce back from a 10-2 loss at the hands of the Chicago Cubs last time out to sit at 1-1 this season. After this series, the Nationals will head on the road for a series against the Philadelphia Phillies.
Jacob Young and Brady House each have a home run and two RBIs while Nasim Nunez and CJ Abrams each have 2 RBIs as well on the year. James Wood’s logged a solo homer while Joey Wiemer also has 3 hits with a solo home run as well this season.
The Chicago Cubs come into this game looking to build on their win over Washington from Saturday to get to 1-1 on the year. After this series, the Cubs will take on the Los Angeles Angels at home.
Ian Happ has a home run and a team-high 3 RBIs while Pete Crow-Armstrong and Michael Busch each have 4 hits with PCA logging 2 RBIs and Busch adding 2 doubles with an RBI. Miguel Amaya has a pair of hits with an RBI as well this season.
I’m on the Cubs here. Irvin has been getting crushed by the Cubs in his career and I just don’t see him being able to match what Imanaga’s going to crank out in this game. I think the Cubs win the series in emphatic fashion, so give me Chicago here.