Chicago Cubs (58-45) vs. Pittsburgh Pirates (53-51) July 25, 2026 6:40 pm EDT The Line: Pittsburgh Pirates -136 / Chicago Cubs 113; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Cubs vs Pirates Prediction for this MLB matchup on Saturday, July 25 th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.
The Pittsburgh Pirates have a 53-51 record this season and are sitting in the 3rd place of the NL Central. They have a 27-25 home record and are coming off a 2-3 home loss against the Cubs. They will face the Dbacks and the Reds next.
The Pittsburgh Pirates have a .260 batting average this season, .338 OBP and .422 Slugging percentage. Pittsburgh’s pitching staff has a 4.23 ERA and 1.30 WHIP. Nick Gonzales is the team’s best hitter with a .312 batting average. Brandon Lowe leads the team in RBI with 65, adding a team-high 21 home runs.
Paul Skenes (R) is the projected starting pitcher for the Pittsburgh Pirates, and he has a 9-8 record, 3.43 ERA and 1.04 WHIP.
The Chicago Cubs have a 58-45 record this season and are sitting in the 2nd place of the NL Central. They have a 28-23 away record and are coming off a 3-2 road win against the Pirates. They will face the Cardinals and the Yankees next.
The Chicago Cubs have a .244 batting average this season, .337 OBP and .411 Slugging percentage. Chicago’s pitching staff has a 4.23 ERA and 1.27 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .285 batting average, adding a team-high 22 home runs. Dansby Swanson leads the team in RBI with 59.
Shota Imanaga (L) is the projected starting pitcher for the Chicago Cubs, and he has a 6-8 record, 3.91 ERA and 1.11 WHIP.
The Cubs have won their last three meetings against the Pirates and are 5-2 in their last 7 visits in Pittsburgh.
In this Cubs vs Pirates Prediction, the Pirates are coming as -135 home favorites. I like the Pirates in a bounce back spot at home today with Skenes on the mound, who has been back on track lately after a long slump, having given up two runs or less in each of his last three starts. Imanaga has also been in good form but will face the second-best offense in baseball and I don’t trust him on the road and the Pirates have been torching lefties in their last 10 games, averaging 6.9 runs per game. Take the Pirates in this one.