Arizona Diamondbacks (15-12) vs. Milwaukee Brewers (14-13) April 28, 2026 7:40 pm EDT The Line: Milwaukee Brewers -118 / Arizona Diamondbacks -102; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Diamondbacks vs Brewers Prediction for this MLB matchup on Tuesday, April 28 th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.
The Milwaukee Brewers have a 14-13 record this season and are sitting in the fifth place of the NL Central. They have an 8-7 home record and are coming off a 5-0 win at home against the Pirates. Their previous three games were a 3-6 and a 0-6 loss at home against the Pirates, and a 4-5 loss on the road to the Tigers .
The Brewers have a .231 batting average this season, .329 OBP and .349 Slugging percentage. Milwaukee’s pitching staff has a 3.82 ERA and 1.30 WHIP. William Contreras is the team’s best hitter with a .263 batting average. Garrett Mitchell leads the team in RBI with 19, and Gary Sanchez adds a team‑high 5 home runs.
Chad Patrick (R) is the projected starting pitcher for the Brewers, and he has a 1-1 record, 2.35 ERA and 1.26 WHIP.
The Arizona Diamondbacks have a 15-12 record this season and are sitting in the third place of the NL West. They have a 6-6 away record and are coming off a 12-7 win at home against the Padres. Their previous three games were a 4-6 loss at home against the Padres, and a 1-4 loss and an 11-7 win at home against the White Sox.
The Diamondbacks have a .255 batting average this season, .310 OBP and .426 Slugging percentage. Arizona’s pitching staff has a 4.53 ERA and 1.32 WHIP. Corbin Carroll is the team’s best hitter with a .287 batting average. Ildemaro Vargas leads the team in RBI with 20, also adding a team‑high 6 home runs.
Merrill Kelly (R) is the projected starting pitcher for the Diamondbacks, and he has a 1-1 record, 9.31 ERA and 2.28 WHIP.
The Diamondbacks are 4-2 in their last 6 meetings against the Brewers and are 4-3 in their last 7 visits in Milwaukee.
In this Diamondbacks vs Brewers Prediction, the Brewers are coming as -109 home favorites. Both teams have not been in good form lately, as they are 1-4 and 2-4 in their last 5 and 6 games respectively, but the Brewers have a pitching advantage today, as Chad Patrick goes up against a struggling Merrill Kelly. Patrick has been almost unhittable lately, having given up just two runs across his last four starts, while Kelly has given up 10 runs in his two starts this season. On top of that, Milwaukee has both a better bullpen and is better against right-handed pitching, so this sets up as a nice home win in this matchup. Take the Brewers on the moneyline.