NY Yankees (88-64) vs. Arizona Diamondbacks (80-73) September 18, 2026 9:40 pm EDT The Line: Arizona Diamondbacks 109 / NY Yankees -131; Over/Under: 8 (Get latest betting odds)
The New York Yankees and Arizona Diamondbacks meet Friday in MLB action at Chase Field. Here’s a Diamondbacks vs. Yankees Prediction. This article will include a Diamondbacks vs. Yankees Pick.
The New York Yankees are 88-64 this year and play the Rays and Orioles next. The New York Yankees are batting .235 on the season, with a .312 OBP and a .409 slugging percentage. The New York Yankees’ pitching staff has a 3.19 ERA and a 1.16 WHIP. Ben Rice leads the New York Yankees with 142 hits and 92 RBI, while Cody Bellinger and Jazz Chisholm Jr. have combined for 236 hits and 126 RBI.
Gerrit Cole gets the ball for the New York Yankees, and he is 8-9 with a 3.67 ERA and 117 strikeouts this season. Cole is 3-2 with a 1.96 ERA and 43 strikeouts in his career against the Arizona Diamondbacks.
The Arizona Diamondbacks are 80-73 on the year and play the Rockies and Padres next. The Arizona Diamondbacks are batting .244 on the season, have a .316 OBP, and have a .397 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.09 ERA and a 1.28 WHIP. Gabriel Moreno leads the Arizona Diamondbacks with 136 hits and 75 RBI, while Geraldo Perdomo and Ketel Marte have combined for 265 hits and 124 RBI.
Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he is 15-6 with a 2.62 ERA and 135 strikeouts this season. Rodriguez is 9-6 with a 2.80 ERA and 120 strikeouts in his career against the New York Yankees.
The Yankees are favored because they’re the Yankees, and it doesn’t hurt that Cole is on the mound. However, we’re getting plus money despite the Diamondbacks side that needs a win to stay in the wild card race. Rodriguez has also been one of the best pitchers in baseball with a 2.62 ERA and 1.22 WHIP through 178.1 innings. At home, Rodriguez has a 2.74 ERA and a .232 allowed batting average. The Diamondbacks have won 8 of the last 11 games Rodriguez has pitched. I’m grabbing the more favorable price with the Diamondbacks in what’s a must-win game.