Cleveland Guardians (1-0) vs. Seattle Mariners (0-1) March 27, 2026 9:40 pm EDT The Line: Seattle Mariners -171 / Cleveland Guardians 141; Over/Under: 7 (Get latest betting odds)
In this article, we will formulate a Guardians vs Mariners Prediction for this MLB matchup on Friday, March 27 th . Let’s take a look at the prediction for this MLB matchup.
The Seattle Mariners have a 0-1 record this season and are sitting on the last place of the AL West. They are coming off a 6-4 home defeat by the Guardians and their previous three games were a 10-3 away loss to the Padres, a 4-2 away win over the White Sox, and a 7-1 home loss to the Cubs in spring training.
The Mariners have a .188 batting average this season, .235 OBP and .625 Slugging percentage. Seattle’s pitching staff has a 6.00 ERA and 1.56 WHIP. Brendan Donovan leads the Mariners with 1 hit, and he is the team’s best hitter with a .500 batting average. Dominic Canzone leads the team in RBI with 2, adding a team-high 2 home runs.
George Kirby (R) is the projected starting pitcher for the Mariners, and last season he had a 10-8 record, 4.21 ERA and 1.19 WHIP.
The Cleveland Guardians have a 1-0 record this season and are sitting on the second place of the AL Central. They are coming off a 6-4 away win over the Mariners and their previous three games were a 10-5 away win over the Diamondbacks, a 7-0 away win over the Diamondbacks, and an 8-2 home win over the Reds in spring training.
The Guardians have a .316 batting average this season, .366 OBP and .579 Slugging percentage. Cleveland’s pitching staff has a 4.00 ERA and 0.89 WHIP. Rhys Hoskins leads the Guardians with 1 hit, and he is the team’s best hitter with a 1.000 batting average. Jose Ramirez leads the team in RBI with 2, and Chase DeLauter added a team-high 2 home runs.
Gavin Williams (R) is the projected starting pitcher for the Guardians, and last season he had a 12-5 record, 3.06 ERA and 1.27 WHIP.
Both teams are tied 5-5 in their last 10 meetings, but the Mariners are 3-1 in their last 4 meetings in Seattle. Over is 8-3 in their last 11 meetings.
In this Guardians vs Mariners Prediction, the Mariners are coming as -165 home favorites. The Mariners are looking for the bounce-back wins and the first one of the season by putting Kirby on the mound, who had been shaky at best last season. The Guardians are putting Gavin Williams on the mound, who had very good numbers last season overall and was excellent in his two starts against the Mariners, with just 3 earned runs in 11 innings pitched. The Guardians’ bullpen also looked great yesterday with just one earned run so I like the Guardians as road dogs in this spot. Take the Guardians on the moneyline for plus money.