Seattle Mariners (21-23) vs. Houston Astros (17-27) May 14, 2026 2:10 pm EDT The Line: Houston Astros 109 / Seattle Mariners -131; Over/Under: 9 (Get latest betting odds)
In this article, we will formulate a Mariners vs Astros Prediction for this MLB matchup on Thursday, May 14 th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The Houston Astros have a 17-27 record this season and are sitting in the fourth place of the AL West. They have a 10-12 home record and are coming off a 4-3 win at home against the Mariners. They will face the Rangers and the Twins next.
The Astros have a .257 batting average this season, .332 OBP and .421 Slugging percentage. Houston’s pitching staff has a 5.54 ERA and 1.58 WHIP. Yordan Alvarez is the team’s best hitter with a .309 batting average, also leading the team in RBI with 29 and adding a team‑high 13 home runs.
Mike Burrows (R) is the projected starting pitcher for the Astros, and he has a 2-4 record, 5.04 ERA and 1.48 WHIP.
The Seattle Mariners have a 21-23 record this season and are sitting in the third place of the AL West. They have a 9-12 away record and are coming off a 3-4 loss on the road against the Astros. They will face the Padres and the White Sox next.
The Mariners have a .230 batting average this season, .320 OBP and .380 Slugging percentage. Seattle’s pitching staff has a 3.63 ERA and 1.23 WHIP. Randy Arozarena is the team’s best hitter with a .306 batting average. Luke Raley leads the team in RBI with 24, also adding a team‑high 9 home runs.
Luis Castillo (R) is the projected starting pitcher for the Mariners, and he has a 0-4 record, 6.57 ERA and 1.62 WHIP.
The Mariners are 9-1 in their last 10 meetings against the Astros and are 5-1 in their last 6 visits in Houston.
In this Mariners vs Astros Prediction, the Brewers are coming as -150 home favorites. I don’t trust either pitcher in this matchup, that is why I will go once again with the over in this one. Both pitchers have a combined 11.61 ERA, with Castillo being a dumpster fire for the Mariners lately, with 15 earned runs across his last three starts. Both pitchers had 6 and 7 earned runs in their previous start against the other team this season and the Astros have the league’s worst bullpen. Take the over 9 runs in this one.