Seattle Mariners (19-21) vs. Chicago White Sox (18-21) May 10, 2026 2:10 pm EDT The Line: Chicago White Sox 109 / Seattle Mariners -131; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Mariners vs White Sox Prediction for this MLB matchup on Sunday, May 10 th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The Chicago White Sox have a 18-21 record this season and are sitting in the third place of the AL Central. They have an 8-9 home record and are coming off a 6-1 win at home against the Mariners. They will face the Royals and the Cubs next.
The White Sox have a .232 batting average this season, .324 OBP and .391 Slugging percentage. Chicago’s pitching staff has a 4.32 ERA and 1.37 WHIP. Chase Meidroth is the team’s best hitter with a .277 batting average. Munetaka Murakami leads the team in RBI with 29, also adding a team‑high 15 home runs.
Davis Martin (R) is the projected starting pitcher for the White Sox, and he has a 5-1 record, 1.64 ERA and 1.02 WHIP.
The Seattle Mariners have a 19-21 record this season and are sitting in the second place of the AL West. They have a 7-10 away record and are coming off a 1-6 loss on the road against the White Sox. They will face the Astros and the Padres next.
The Mariners have a .230 batting average this season, .320 OBP and .379 Slugging percentage. Seattle’s pitching staff has a 3.81 ERA and 1.24 WHIP. Randy Arozarena is the team’s best hitter with a .278 batting average. Luke Raley leads the team in RBI with 23, also adding a team‑high 8 home runs.
Logan Gilbert (R) is the projected starting pitcher for the Mariners, and he has a 2-3 record, 4.30 ERA and 1.30 WHIP.
The Mariners are 8-2 in their last 10 meetings against the White Sox and are 5-2 in their last 7 meetings in Chicago.
In this Mariners vs White Sox Prediction, the Mariners are coming as -130 road favorites. The White Sox destroyed the Mariners yesterday and are home dogs today with Davis Martin on the mound, who has a 1.64 ERA and has been unhittable at home with a 0.77 home ERA. On top of that, the White Sox also have a better offense and Gilbert has been up and down this season, so I like the value with the home team in this one. Take the White Sox on the moneyline for plus money.