Seattle Mariners (14-15) vs. Minnesota Twins (12-16) April 27, 2026 7:40 pm EDT The Line: Minnesota Twins +123 / Seattle Mariners -136; Over/Under: 8.5 (Get latest betting odds)
The Seattle Mariners and the Minnesota Twins meet Monday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. Minnesota Twins prediction.
The Seattle Mariners will send out Luis Castillo for the start here and Castillo is 0-1 with a 5.01 ERA and 23 strikeouts this season. In his last five starts against the Twins, Castillo is 0-1 with a 3.64 ERA and 27 strikeouts. Connor Prielipp will start here for the Twins and is 0-0 with a 4.50 ERA and 6 strikeouts this season. This will be Prielipp’s first career start against the Mariners.
The Seattle Mariners come into this game looking to add on to their 3-2 win over St. Louis last time out to sit at 14-15 this season. After this series, the Mariners will head home for a set against the Kansas City Royals.
Brendan Donovan has 17 hits with 3 doubles, 3 home runs and 8 RBIs while Luke Raley has 5 home runs and 13 RBIs this season. Cole Young’s added 27 hits with 3 doubles, a triple, 3 home runs and 14 RBIs and Cal Raleigh has 23 hits with 4 doubles, 6 home runs and 15 RBIs as well this season. Randy Arozarena has 29 hits with 8 doubles, 2 home runs and 11 RBIs as well on the year. Josh Naylor also has 21 hits with 3 home runs and 11 RBIs as well on the year. Julio Rodriguez has also added 28 hits with 3 doubles, 2 home runs and 10 RBIs.
The Minnesota Twins come into this game looking to shake off their 4-2 loss at the hands of the Tampa Bay Rays last time out to sit at 12-16 this season. After this series, the Twins will take on the Toronto Blue Jays in a series at home.
Byron Buxton has 24 hits with 4 doubles, a triple, 5 home runs and 7 RBIs while Josh Bell’s added 22 hits with 5 doubles, 3 home runs and 16 RBIs. Luke Keaschall has 22 hits with 3 doubles, a homer and 12 RBIs and Matt Wallner has 16 hits with a pair of doubles, 3 home runs and 7 RBIs. Brooks Lee has 5 home runs with 15 RBIs and Victor Caratini has 11 RBIs while Ryan Jeffers has 18 hits with 2 doubles, a triple, 3 home runs and 16 RBIs this season.
I’m on the Mariners here. I just can’t get behind the Twins in their current form. Seattle has been crushing left-handed pitching as of late and this is only the second start at the major league level for Prielipp. Castillo has had some issues with giving up runs in fairness, but I still think he can have a solid start here and all in all, I have to back him here so give me Seattle.