Boston Red Sox (12-17) vs. Toronto Blue Jays (12-16) April 28, 2026 7:07 pm EDT The Line: Toronto Blue Jays 0.0001 / Boston Red Sox 0.0001; Over/Under: 0.0001 (Get latest betting odds)
In this article, we will formulate a Red Sox vs Blue Jays Prediction for this MLB matchup on Tuesday, April 28 th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.
The Toronto Blue Jays have a 12-16 record this season and are sitting in the fourth place of the AL East. They have a 8-8 home record and are coming off a 0-5 home defeat by the Red Sox. Their previous three games were a 4-2 win, a 5-3 win and an 8-6 loss at home against the Guardians.
The Blue Jays have a .249 batting average this season, .308 OBP and .379 Slugging percentage. Toronto’s pitching staff has a 4.47 ERA and 1.33 WHIP. Vladimir Guerrero Jr. is the team’s best hitter with a .330 batting average. Andres Gimenez leads the team in RBI with 16, and Kazuma Okamoto adds a team‑high 5 home runs.
Trey Yesavage (R) is the projected starting pitcher for the Blue Jays and last season he had 1-0 record, 3.21 ERA and a 1.43 WHIP.
The Boston Red Sox have a 12-17 record this season and are sitting in the fifth place of the AL East. They have a 7-9 away record and are coming off a 5-0 road win against the Blue Jays. Their previous three games were a 5-3 win, a 17-1 win and a 3-10 loss on the road against the Orioles .
The Red Sox have a .234 batting average this season, .314 OBP and .356 Slugging percentage. Boston’s pitching staff has a 4.23 ERA and 1.30 WHIP. Wilyer Abreu is the team’s best hitter with a .306 batting average. Willson Contreras leads the team in RBI with 19, also adding a team‑high 6 home runs.
Payton Tolle (L) is the projected starting pitcher for the Red Sox, and he has a 0-0 record, 1.50 ERA and 0.67 WHIP.
The Red Sox are 3-1 in their last 4 meetings against the Blue Jays and both teams are tied 3-3 in their last 6 meetings in Toronto.
In this Red Sox vs Blue Jays Prediction, the Blue Jays are coming as -120 home favorites. Boston kept rolling and shut out the Jays yesterday by 5-0 and are putting Payton Tolle on the mound, whose first start of the season was a quality start against the Yankees. I don’t trust Yesavage in his first start of the season for the Jays and the Red Sox have a better bullpen and a better offense, with the Jays being weaker against left-handed pitching. Give me the Red Sox and the plus money in this one.