Boston Red Sox (5-9) vs. St. Louis Cardinals (8-6) April 12, 2026 2:15 pm EDT The Line: St. Louis Cardinals 0.0001 / Boston Red Sox 0.0001; Over/Under: 0.0001 (Get latest betting odds)
In this article, we will formulate a Red Sox vs Cardinals Prediction for this MLB matchup on Sunday, April 12th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.
The St. Louis Cardinals have a 8-6 record this season and are sitting in the fourth place of the NL Central. They have a 5-3 home record and are coming off a 1-7 home loss against the Red Sox. Their previous three games were a 3-2 home win against the Red Sox, and a 6-1 and a 7-6 road win against the Nationals.
The Cardinals have a .224 batting average this season, .324 OBP and .352 Slugging percentage. St. Louis’ pitching staff has a 4.82 ERA and 1.46 WHIP. Jordan Walker is the team’s best hitter with a .314 batting average, also adding a team‑high 6 home runs and leading the team in RBI with 13.
Andre Pallante (R) is the projected starting pitcher for the Cardinals, and he has a 1-0 record, 1.80 ERA and 1.30 WHIP.
The Boston Red Sox have a 5-9 record this season and are sitting in the fifth place of the AL East. They have a 2-6 away record and are coming off a 7-1 road win against the Cardinals. Their previous three games were a 3-2 road loss against the Cardinals, and a 5-0 and a 3-2 home win against the Brewers.
The Red Sox have a .226 batting average this season, .311 OBP and .341 Slugging percentage. Boston’s pitching staff has a 3.90 ERA and 1.34 WHIP. Wilyer Abreu is the team’s best hitter with a .364 batting average, also adding a team-high 3 home runs and leading the team in RBI with 9.
Brayan Bello (R) is the projected starting pitcher for the Red Sox, and he has a 0-1 record, 9.00 ERA and 2.50 WHIP.
The Red Sox are 5-1 in their last 6 meetings against the Cardinals but the Cardinals are 3-2 in their last 5 home meetings against the Red Sox.
In this Red Sox vs Cardinals Prediction, the Red Sox are coming as -125 road favorites. Both teams are in good form lately with a 3-1 record in their last 4 games, but Bello has been struggling so far for the Red Sox with 8 earned runs in his two starts. On the flip side, Pallante has been excellent in his two starts for the Cardinals, who also have a better offense, so I like them as home dogs in this spot. Take the Cardinals on the moneyline for plus money.