Cincinnati Reds (74-86) vs. Toronto Blue Jays (78-82) September 26, 2026 3:07 pm EDT The Line: Toronto Blue Jays -168 / Cincinnati Reds 138; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Reds vs Blue Jays Prediction for this MLB matchup on Saturday, September 26 th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.
The Toronto Blue Jays have a 78-82 record this season and are sitting in the 5th place of the AL East. They have a 41-38 home record and are coming off a 6-5 home win against the Reds.
The Toronto Blue Jays have a .248 batting average this season, .311 OBP and .382 Slugging percentage. Toronto’s pitching staff has a 3.92 ERA and 1.30 WHIP. Vladimir Guerrero Jr. is the team’s best hitter with a .262 batting average. Kazuma Okamoto leads the team in RBI with 92, adding a team-high 33 home runs.
Trey Yesavage (R) is the projected starting pitcher for the Blue Jays, and he has a 5-5 record, 3.67 ERA and 1.13 WHIP.
The Cincinnati Reds have a 74-86 record this season and are sitting in the 5th place of the NL Central. They have a 36-43 away record and are coming off a 5-6 road loss against the Blue Jays.
The Cincinnati Reds have a .229 batting average this season, .305 OBP and .395 Slugging percentage. Cincinnati’s pitching staff has a 4.85 ERA and 1.45 WHIP. Elly De La Cruz is the team’s best hitter with a .285 batting average. Sal Stewart leads the team in RBI with 111, adding a team-high 32 home runs.
Rhett Lowder (R) is the projected starting pitcher for the Reds, and he has a 6-12 record, 6.01 ERA and 1.55 WHIP.
The Blue Jays are 6-3 in their last 9 meetings against the Reds and have won two of their last three meetings in Toronto.
In this Reds vs Blue Jays Prediction, the Blue Jays are coming as -160 home favorites. I like the Jays in this one as they have the pitching edge with Trey Yesavage going up against Rhett Lowder. Yesavage has just two earned runs in his last three starts, while Lowder has been atrocious on the road with a 4-8 record and 7.44 ERA. On top of that, during their last 5 games, the Jays have a better offense and a 1.88 bullpen ERA. Take the Jays to win this one.