Chicago White Sox (24-22) vs. Seattle Mariners (22-26) May 18, 2026 9:40 pm EDT The Line: Seattle Mariners -175 / Chicago White Sox +144; Over/Under: 7 (Get latest betting odds)
The Chicago White Sox and the Seattle Mariners meet Monday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs. Seattle Mariners prediction.
The Chicago White Sox will send out Noah Schultz for the start here and Schultz is 2-2 with a 4.91 ERA and 26 strikeouts this season. This will be Schultz’s first career start against the Mariners. Bryan Woo will start here for the Mariners and is 3-2 with a 3.91 ERA and 47 strikeouts this season. In his career, Woo is 1-0 with a 1.74 ERA and 24 strikeouts against the White Sox.
The Chicago White Sox come into this game looking to add on to their 9-8 win over the Cubs last time out to sit at 24-22 this season. After this series, the White Sox will head on the road for a series against the San Francisco Giants.
Munetaka Murakami has 38 hits with 17 home runs and 32 RBIs while Miguel Vargas has 40 hits with 7 doubles, a triple, 11 home runs and 29 RBIs and Colson Montgomery has 39 hits with 8 doubles, 13 home runs and 31 RBIs. Luisangel Acuna has 15 hits and Tristan Peters has 27 hits with 4 doubles so far this season. Chase Meidroth also has 43 hits with 9 doubles, 3 home runs and 10 RBIs this year.
The Seattle Mariners come into this game looking to bounce back from an 8-3 loss at the hands of the San Diego Padres last time out to sit at 22-26 this season. After this series, the Mariners will head on the road for a series against the Kansas City Royals.
Luke Raley has 10 home runs and 27 RBIs this season. Cole Young’s added 42 hits with 8 doubles, a triple, 3 home runs and 26 RBIs and Cal Raleigh has 26 hits with 4 doubles, 7 home runs and 18 RBIs as well this season. Randy Arozarena has 52 hits with 11 doubles, 4 home runs and 18 RBIs as well on the year. Josh Naylor also has 44 hits with 5 home runs and 20 RBIs as well on the year. Julio Rodriguez has also added 48 hits with 9 doubles, 7 home runs and 20 RBIs.
I’m on the Mariners in this one. There’s no denying that the White Sox have been the hotter team, but it still looks like Schultz has had some issues adjusting to the Major League level, and the Mariners just have a significant edge in starting pitching with Woo going here and bouncing back from a couple of rough starts at the end of April/early May. I think the Mariners take the opener here so give me Seattle.