Seattle Mariners (11-15) vs. St. Louis Cardinals (14-10) April 24, 2026 8:15 pm EDT The Line: St. Louis Cardinals +136 / Seattle Mariners -148; Over/Under: 8 (Get latest betting odds)
The Seattle Mariners and the St. Louis Cardinals meet Friday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. St. Louis Cardinals prediction.
The Seattle Mariners will send out George Kirby for the start here and Kirby is 3-2 with a 2.97 ERA and 27 strikeouts this sesaon. In his career, Kirby is 1-0 with a 4.50 ERA and 7 strikeouts against the Cardinals. The St. Louis Cardinals will trot out Andre Pallante here and Pallante is 2-1 with a 4.05 ERA and 12 strikeouts this season. This will be Pallante’s first career start against the Mariners.
The Seattle Mariners come into this game looking to add on to their 5-4 win over the Athletics last time out to sit at 11-15 this season. After this series, the Mariners will head on the road for a series against the Minnesota Twins.
Brendan Donovan has 17 hits with 3 doubles, 3 home runs and 8 RBIs while Luke Raley has 5 home runs and 13 RBIs this season. Cole Young’s added 21 hits with 2 doubles, a triple, 2 home runs and 11 RBIs and Cal Raleigh has 20 hits with 4 doubles, 5 home runs and 14 RBIs as well this season. Randy Arozarena has 27 hits with 6 doubles, 2 home runs and 10 RBIs as well on the year. Josh Naylor also has 18 hits with 2 home runs and 10 RBIs as well on the year. Julio Rodriguez has also added 24 hits with 3 doubles, a home run and 8 RBIs.
The St. Louis Cardinals come into this game looking to shake off a 4-1 loss at the hands of the Miami last time out to sit at 14-10 this season. After this series, St. Louis will take on the Pittsburgh Pirates on the road.
Jordan Walker leads the Cardinals with 26 hits, 4 doubles, 8 home runs and 16 RBIs while Alec Burleson has 25 hits with 6 doubles, 3 home runs and 17 RBIs. JJ Wetherholt has 19 hits with 3 home run and 11 RBIs while Ivan Herrera has 20 hits with 4 doubles and 12 RBIs. Nolan Gorman has 16 hits with 3 home runs and 15 RBIs this season.
I’m on the Mariners here. I think that Pallante is the weak link of the Cardinals’ rotation and I think the Mariners are starting to pick it up after a slow start out of the gate at the plate. I think Kirby is the far stronger starting option in this game and I still believe the Mariners have one of the better bullpens in baseball across the board. Give me the Mariners in this one.