Cleveland Guardians (26-22) vs. Detroit Tigers (20-27) May 18, 2026 6:40 pm EDT The Line: Detroit Tigers -149 / Cleveland Guardians 123; Over/Under: 8.5 (Get latest betting odds)
The Cleveland Guardians and Detroit Tigers meet Monday in MLB action at Comerica Park. Here’s a Tigers vs. Guardians Prediction. This article will include a Tigers vs. Guardians Pick.
The Cleveland Guardians are 26-22 on the year and play the Phillies and Nationals next. The Cleveland Guardians are batting. 232 on the season, have a .327 OBP, and have a .378 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.88 ERA and a 1.27 WHIP. Chase DeLauter leads the Cleveland Guardians with 44 hits and 28 RBI while Brayan Rocchio and Jose Ramirez have combined for 83 hits and 45 RBI.
Slade Cecconi gets the ball for the Cleveland Guardians, and he is 2-4 with a 5.60 ERA and 38 strikeouts this season. Cecconi is 1-1 with a 2.25 ERA and 11 strikeouts in his career against the Detroit Tigers.
The Detroit Tigers are 20-27 on the year and play the Angels and Orioles next. The Detroit Tigers are batting .239 on the season and have a .321 OBP, and a .381 slugging percentage. The Detroit Tigers’ pitching staff has a 3.94 ERA and a 1.30 WHIP. Riley Greene leads the Detroit Tigers with 54 hits and 23 RBI, while Colt Keith and Kevin McGonigle have combined for 87 hits and 22 RBI.
Framber Valdez gets the ball for the Detroit Tigers, and he is 2-2 with a 4.32 ERA and 42 strikeouts this season. Valdez is 5-0 with a 2.30 ERA and 22 strikeouts in his career against the Cleveland Guardians.
The Guardians are coming off a hell of a week and the same can’t be said for the Tigers. I’d look at Cleveland in this spot, but I’m going with the over. Cecconi has a 5.60 ERA and 1.58 WHIP through 45 innings, while Valdez has a 4.32 ERA and 1.36 WHIP in 50 innings. These arms have combined for 34 walks as well. In 30 road innings, Cecconi has a 6.60 ERA and a .311 allowed batting average. The Guardians enter this series hot offensively. I expect some offense. Give me the over on Monday night.