Minnesota Twins (26-27) vs. Chicago White Sox (26-26) May 25, 2026 2:10 pm EDT The Line: Chicago White Sox -106 / Minnesota Twins -114; Over/Under: 8 (Get latest betting odds)
The Minnesota Twins and Chicago White Sox meet Monday in MLB action at Rate Field. Here’s a White Sox vs. Twins Prediction. This article will include a White Sox vs. Twins Pick.
The Minnesota Twins are 26-27 on the year and play the White Sox and Pirates next. The Minnesota Twins are batting .240 on the season and have a .325 OBP, and a .389 slugging percentage. The Minnesota Twins pitching staff has a 4.19 ERA and a 1.32 WHIP. Byron Buxton leads the Minnesota Twins with 49 hits and 26 RBI, while Brooks Lee and Josh Bell have combined for 87 hits and 56 RBI.
Zebby Matthews gets the ball for the Minnesota Twins, and he is 1-1 with a 1.38 ERA and 11 strikeouts this season. Matthews is 0-0 with a 4.22 ERA and 9 strikeouts in his career against the Chicago White Sox.
The Chicago White Sox are 26-26 on the year and play the Twins and Tigers next. The Chicago White Sox are batting .232 on the season, have a .322 OBP, and have a .399 slugging percentage. The Chicago White Sox pitching staff has a 4.54 ERA and a 1.37 WHIP. Chase Meidroth leads the Chicago White Sox with 48 hits and 13 RBI, while Munetaka Murakami and Miguel Vargas have combined for 87 hits and 67 RBI.
Anthony Kay gets the ball for the Chicago White Sox, and he is 3-1 with a 4.27 ERA and 34 strikeouts this season. This will be Kay’s first career game against the Minnesota Twins.
The Twins have put together a nice little winning streak but there are questions about how long it will last. The Twins have underachieved for the most part up to this point and while Matthews has been solid, he’s pitched just 13 innings. The White Sox have had value up to this point and they’ve played their best ball at home. The White Sox have won 6 of the last 9 games Kay has pitched and through 22 home innings he has a 3.68 ERA. Give me the White Sox at home with the cheap price, as I simply trust them more.