Buffalo Bulls (1-1) vs. Penn State Nittany Lions (2-0) September 19, 2026 12:00 pm EDT The Line: Penn State Nittany Lions 0.0001 / Buffalo Bulls 0.0001; Over/Under: 49.5 (Get latest betting odds)
In this article we will formulate a Penn State vs Buffalo prediction for this College Football game on Saturday, September 19th at Beaver Stadium in University Park, Pennsylvania. Let’s take a look at the prediction for this Week 3 matchup.
The Penn State Nittany Lions are 2-0 this season after they defeated Temple by a score of 27-9 in week two. Penn State led 10-3 at halftime and 27-3 in the fourth, but they blew the cover by allowing a touchdown with 1:56 left in the game. The Nittany Lions out gained Temple by a total of 416-283, went 6-12 on third downs, and won the turnover battle by a total of 1-0 in the game. Rocco Becht threw for 268 yards and three touchdowns, while Benjamin Brahmer caught five passes for 79 yards and two scores. Carson Hansen rushed 19 times for 84 yards in the win.
Prior to that game, Penn State defeated Marshall by a score of 45-0 in week one. Penn State has scored 36.0 points per game with 296.0 passing yards and 155.5 rushing yards per game, while they have allowed 4.5 points against per game this season. Rocco Becht has thrown for 539 yards, seven touchdowns, and zero interceptions, while Koby Howard has nine receptions for 229 yards and one score this season.
The Buffalo Bulls are 1-1 this year after they lost to FIU by a score of 33-20 in week two. Buffalo trailed 21-6 at halftime and cut the deficit to 21-14 early in the third, but they allowed the next 12 points to seal the loss. The Bulls were out gained by a total of 540-308, went 4-17 on third downs, and lost the turnover battle by a total of 3-1 in the game. Jason Wright threw for 185 yards, two touchdowns, and one interception, while Chance Morrow caught 11 passes for 170 yards and two scores. Terrance Shelton Jr rushed eight times for 29 yards in the loss.
Prior to that game, Buffalo defeated Albany by a score of 21-17 in week one. The Bulls have scored 20.5 points per game with 217.5 passing yards and 103.5 rushing yards per game, while they have allowed 25.0 points against per game this season. Jason Wright has thrown for 185 yards, two touchdowns, and one interception, while Chance Morrow has 18 catches for 218 yards and five scores this year.
Penn State comes into this matchup after failing to cover against Temple and they struggled to pull away in that win. The Nittany Lions will be back at home for this one and should get an easy win. Buffalo lost by 13 to FIU last week and barely got by a FCS school in week one. The Bulls have one very good wide receiver, but the rest of their offense has not played well. Penn State should be able to shut down this Buffalo offense, but this is a lot of points for a school that only scored 27 against Temple. Take the Bulls and the points here.