Houston Astros (11-19) vs. Baltimore Orioles (14-15) April 29, 2026 6:35 pm EDT The Line: Baltimore Orioles -126 / Houston Astros +104; Over/Under: 9 (Get latest betting odds)
The Houston Astros and the Baltimore Orioles meet Wednesday in MLB action from Camden Yards. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Baltimore Orioles prediction.
The Houston Astros will send out Peter Lambert for the start here and Lambert is 1-1 with a 3.27 ERA and 16 strikeouts this season. This will be Lambert’s first career start against the Orioles. Chris Bassitt will start for the Orioles in this one and is 1-2 with a 6.75 ERA and 10 strikeouts this season. In his last five starts against the Astros, Bassitt is 2-3 with a 4.34 ERA and 19 strikeouts.
The Houston Astros come into this game looking to bounce back from their 5-3 loss at the hands of the Baltimore Orioles last time out to sit at 11-19 on the year. After this series, the Astros will head on the road for a set against the Boston Red Sox.
Entering Tuesday, Yordan Alvarez has 38 hits with 9 doubles, 11 home runs and 26 RBIs while Christian Walker has 30 hits with 8 doubles, 7 home runs and 23 RBIs on the year. Jose Altuve’s chipped in 27 hits with 7 doubles, 3 home runs and 8 RBIs and Carlos Correa has 27 hits with 7 doubles, 2 home runs and 14 RBIs. Cam Smith also has 21 hits with 5 doubles, 3 home runs and 11 RBIs. Yainer Diaz also has 17 hits with 3 doubles, 2 home runs and 12 RBIs.
The Baltimore Orioles come into this game looking to build on their win over Houston from Tuesday to sit at 14-15 this season. After this series, the Orioles will head on the road for a series against the New York Yankees.
Going into Tuesday, Taylor Ward has 34 hits with 13 doubles and 11 RBIs while Gunnar Henderson has 25 hits with 4 doubles, 9 home runs and 18 RBIs and Pete Alonso has 21 hits with 6 doubles, 3 home runs and 10 RBIs. Adley Rutschman has 17 hits with 6 doubles, 3 home runs and 11 RBIs. Jeremiah Jackson has 24 hits with 2 doubles, 5 home runs and 19 RBIs while Dylan Beavers also has 17 hits with 3 doubles, 2 home runs and 8 RBIs.
I’m on the over here. Lambert pitched well in his last start but I don’t really trust him long term as I feel like I need to see more than just 11 innings of work and the Astro bullpen behind him is still brutal. On the flipside, Chris Bassitt hasn’t looked good for much of the year and the Astro bats have started to heat up. I think this is going to be a high-scoring game so give me the over here.