St. Louis Cardinals (29-23) vs. Milwaukee Brewers (31-20) May 26, 2026 7:40 pm EDT The Line: Milwaukee Brewers -181 / St. Louis Cardinals 149; Over/Under: 8 (Get latest betting odds)
In this article, we will formulate a Cardinals vs Brewers Prediction for this MLB matchup on Tuesday, May 26 th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.
The Milwaukee Brewers have a 31-20 record this season and are sitting in the first place of the NL Central. They have a 17-11 home record and are coming off a 5-1 home win against the Cardinals. They will face the Astros and the Giants next.
The Brewers have a .248 batting average this season, .334 OBP and .364 Slugging percentage. Milwaukee’s pitching staff has a 3.27 ERA and 1.20 WHIP. William Contreras is the team’s best hitter with a .304 batting average, also leading the team in RBI with 31. Jake Bauers adds a team-high 7 home runs.
Kyle Harrison (L) is the projected starting pitcher for the Brewers, and he has a 5-1 record, 1.77 ERA and 1.07 WHIP.
The St. Louis Cardinals have a 29-23 record this season and are sitting in the second place of the NL Central. They have a 16-10 away record and are coming off a 1-5 road defeat against the Brewers. They will face the Cubs and the Rangers next.
The Cardinals have a .239 batting average this season, .320 OBP and .387 Slugging percentage. St. Louis’ pitching staff has a 4.23 ERA and 1.38 WHIP. Jordan Walker is the team’s best hitter with a .297 batting average, also leading the team in RBI with 42 and adding a team-high 15 home runs.
Michael McGreevy (R) is the projected starting pitcher for the Cardinals, and he has a 3-3 record, 2.40 ERA and 0.99 WHIP.
Both teams are tied 4-4 in their last 8 meetings but the Brewers are 4-1 in their last 5 meetings in Milwaukee.
In this Cardinals vs Brewers Prediction, the Brewers are coming as -180 home favorites. The Brewers dominated the opening game of the series and have the pitching edge today with the red-hot Kyle Harrison on the bump, who is coming off back-to-back shutouts. On top of that, the Brewers have a better bullpen and a better offense, with the Cardinals being weaker against lefties. Take the Brewers to win this one at home.