Arizona Diamondbacks (39-38) vs. St. Louis Cardinals (41-34) June 22, 2026 7:45 pm EDT The Line: St. Louis Cardinals -144 / Arizona Diamondbacks +119; Over/Under: 8.5 (Get latest betting odds)
The Arizona Diamondbacks and the St. Louis Cardinals meet Monday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Arizona Diamondbacks vs. St. Louis Cardinals prediction.
The Arizona Diamondbacks will send out Merrill Kelly for the start here and Kelly is 5-6 with a 5.81 ERA and 42 strikeouts this season. The St. Louis Cardinals will start Andre Pallante and Pallante is 8-4 with a 3.76 ERA and 62 strikeouts this season.
The Arizona Diamondbacks come into this game looking to shake off a 4-2 loss at the hands of Minnesota in their last game to sit at 39-38 this season. After this series, the Diamondbacks will head on the road for a series against the Tampa Bay Rays.
Corbin Carroll has 77 hits including 16 doubles, 9 triples, 13 home runs and 42 RBIs. Ketel Marte has 76 hits with 16 doubles, 12 home runs and 46 RBIs and Geraldo Perdomo has 61 hits, with 10 doubles, 3 triples, 4 home runs and 27 RBIs as well this season. Nolan Arenado also has 58 hits with 12 doubles, 8 home runs and 31 RBIs and Jose Fernandez has 42 hits with 3 home runs and 15 RBIs this season. Ildemaro Vargas also has 63 hits with 10 doubles, 2 triples, 7 home runs and 42 RBIs.
The St. Louis Cardinals come into this game looking to add on to their 12-10 win over Kansas City last time out to sit at 41-34 this season. After this series, the Cardinals will take on the Miami Marlins in a series at home.
Jordan Walker leads the Cardinals with 85 hits, 16 doubles, 18 home runs and 58 RBIs while Alec Burleson has 84 hits with 19 doubles, 13 home runs and 55 RBIs. JJ Wetherholt has 74 hits with 12 home runs and 34 RBIs while Ivan Herrera has 73 hits with 13 doubles, 10 home runs and 38 RBIs. Nolan Gorman has 39 hits with 7 home runs and 26 RBIs this season. Masyn Winn’s added 62 hits with 11 doubles and 31 RBIs and Nathan Church has 47 hits with 5 home runs and 19 RBIs this season.
I’m on the Cardinals in this one. The Cardinals have just been the better team in the month of June in my opinion, and Andre Pallante has quietly been one of St. Louis’ better options as a starter through the first half of the season so far. I think the Cardinals add another win to their docket here as Merrill Kelly has issues navigating the Cardinals and Arizona’s lack of run support comes back to bite Kelly here. Give me the Cards.